High seroprevalence and associated risk factors for hepatitis B virus infection among pregnant women living with HIV in Mtwara region, Tanzania

Abstract Background Hepatitis B virus (HBV) infection continues to be a global public health problem. As of 2019, there were 296 million people chronically infected with HBV, resulting in nearly 1 deaths from decompensated cirrhosis or hepatocellular carcinoma. The seroprevalence HBV among pregnant women Tanzania was reported range between 3.8 and 8.03%. However, data on HIV-infected is limited. We aimed determine the associated risk factors for selected facilities Mtwara region. This facility-based quantitative cross-sectional study conducted three months (from February April 2022). A structured questionnaire used collect information participants. total 4 ml blood collected screening confirmatory tests using rapid diagnostic automated Enzyme-Linked Immunosorbent Assay (ELISA) tests, respectively. logistic regression model identify significant variables infection. Results Two hundred twenty ( n = 220) living HIV enrolled this study, median age 32.7 years (Interquartile (IQR) 27.6–37.6). chronic, acute infections 10.5%, 10.0%, 0.5%, found that multiparous [aOR 11.99: 95% CI 1.11–129.01, p 0.040], being syphilis 27.65: 9.07–84.30, < 0.001], having viral load 1000 copies/ml above 16.00: 1.70–150.63, 0.015], are independently Conclusions overall which high endemicity. Furthermore, revealed more than four children, HIV-1 ≥ 1000cp/ml,